This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. For prevention of malaria in adults, one dose is usually taken once a week on exactly the same day of the week. Plaquenil arava Chloroquine drug name In the treatment of diseases other than malaria, chloroquine is administered in a much larger dosage and more frequently, usually 250 to 750 mg daily. 1 The occurrence of a characteristic retinopathy following the long-term daily ad- ministration of chloroquine has now been well documented. 2 The fact that the retinal lesion usually develops. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is also occasionally used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus. It is taken by mouth. Common side effects include muscle problems, loss of appetite, diarrhea, and skin rash. Serious A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. One dose is taken beginning 2 weeks before traveling to an area where malaria is common, while you are in the area, and then for 8 weeks after you return from the area. Your doctor will tell you how many tablets to take for each dose. Chloroquine pharmacology Targeting endosomal acidification by chloroquine analogs as a., Chloroquine - Wikipedia Otezla and plaquenil Chloroquine is the prototype anti malarial drug, most widely used to treat all types of malaria except for disease caused by chloroquine resistant Plasmodium falciparum. It is highly effective against erythrocytic forms of Plasmodium vivax, Plasmodium ovale and Plasmodium malariae, sensitive strains of Plasmodium falciparum and gametocytes of Plasmodium vivax. Chloroquine C18H26ClN3 - PubChem. Chloroquine Indications, Side Effects, Warnings -. Hydroxychloroquine DermNet NZ. Clinical pharmacology Chloroquine is rapidly and almost completely absorbed from the gastrointestinal tract, and only a small proportion of the administered dose is found in the stools. Chloroquine is administered orally as chloroquine phosphate. It also can be given by intramuscular injection as chloroquine hydrochloride. Chloroquine is effective against susceptible strains of the malarial parasites Plasmodium vivax, P. ovale, and P. falciparum, as well as certain parasitic worms and amoebas. Some mild side effects may occur, including headache and abdominal cramps, which are common to antimalarials. CLINICAL PHARMACOLOGY. Chloroquine is rapidly and almost completely absorbed from the gastrointestinal tract, and only a small proportion of the administered dose is found in the stools. Approximately 55% of the drug in the plasma is bound to nondiffusible plasma constituents.