Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil vs methotrexate for ra Chloroquine action and target Psoriasis and hydroxychloroquine Low dose naltrexone and plaquenil Side-effects aren't common. However, in some people hydroxychloroquine can cause skin rashes, especially those made worse by sunlight; feeling sick nausea or indigestion; diarrhoea; headaches; bleaching of the hair or mild hair loss; tinnitus ringing in the ears visual problems. It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works. How to use Plaquenil Hydroxychloroquine is usually taken with food. For lupus erythematosus, one or two tablets are usually taken once or twice daily. For rheumatoid arthritis, one to three tablets are usually taken once a day. Hydroxychloroquine can be taken with a glass of milk or a meal to decrease nausea. Follow the directions on your prescription label carefully. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can hydroxychloroquine cause a lupus type rash Lupus - Symptoms and causes - Mayo Clinic, Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Plaquenil maculopathy oct imagesPlaquenil testing icd 10Side effects of hydroxychloroquine medication A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling especially of the face/tongue/throat, dizziness, trouble breathing. This is not a complete list of possible side effects. Plaquenil Oral Uses, Side Effects, Interactions.. Hydroxychloroquine MedlinePlus Drug Information. Hydroxychloroquine Side Effects Common, Severe, Long Term.. In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. As noted, the most common antimalarial used is Plaquenil hydroxychloroquine, which is dosed by weight and used for persistent rashes. Evidence suggests that early use may delay systemic onset of lupus. A known side effect of using antimalarials long term is dark patches on the skin. The Lupus Encyclopedia Thomas Jr. 2014 says this 'One of the potential long-term side-effects of using anti-malarial medications such as hydroxychloroquine Plaquenil, chloroquine, and quinacrine is the development of dark-colored patches on the skin.