Chemical structure of chloroquine

Discussion in 'Aralen' started by AndrewML, 26-Feb-2020.

  1. Despic Moderator

    Chemical structure of chloroquine


    Information also provided for 3,600 nuclides and 4,400 nuclide decay modes. Editor's note: Some chemicals in this database contain more information than others due to the original reason this information was collected and how the compilation was accomplished.

    Hydroxychloroquine and colds Chloroquine plus primaquine

    We have detected that you are are on a small device such as a mobile phone. We recommend you use a larger device to draw your structure. Still want to try? Try rotating the device so that it is in a landscape position. Chloroquine Phosphate. Molecular Formula C 18 H 29 ClN 3 O 4 P; Average mass 417.867 Da; Monoisotopic mass 417.158417 Da; ChemSpider ID 75637 Chloroquine Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. 4 It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. 17 Chloroquine was granted FDA Approval on 31 October 1949. 19

    To resolve this problem, over the years, I compiled chemical names and identifiers into a personal database, cross referencing regulatory and health safety information when possible. While working with material safety data sheets (MSDS), I found that manufacturers sometimes used obscure names for constituent chemicals and I didn't always have a good idea of what I was dealing with.

    Chemical structure of chloroquine

    Chloroquine Ligand page IUPHAR/BPS Guide to PHARMACOLOGY, Chloroquine Phosphate C18H29ClN3O4P ChemSpider

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  5. Amodiaquine is an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties. Similar in structure and activity to chloroquine, amodiaquine is effective against some chloroquine-resistant strains, particularly Plasmodium falciparum, the most deadly malaria parasite. Although the mechanism of plasmodicidal action has not been fully elucidated, like other.

    • Amodiaquine C20H22ClN3O - PubChem.
    • Chloroquine phosphate - DrugBank.
    • Chloroquine diphosphate C18H32ClN3O8P2 ChemSpider.

    Chemical Class An aminoquinoline that is quinoline which is substituted at position 4 by a 5-diethylaminopentan-2-ylamino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoe biasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. It is also being used as an experimental treatment for SARS-CoV-2. Using CATALYST, a three-dimensional QSAR pharmacophore model for chloroquineCQ-resistance reversal was developed from a training set of 17 compounds. These included imipramine 1, desipramine 2, and 15 of their analogues 3−17, some of which fully reversed CQ-resistance, while others were without effect.

     
  6. kunctator Well-Known Member

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Plaquenil Hydroxychloroquine Sulfate Plaquenil Uses, Dosage & Side Effects - Allergic reaction to plaquenil DailyStrength
     
  7. Ict Moderator

    Please make sure that Javascript and cookies are enabled on your browser and that you are not blocking them from loading. Nightmares plaquenil lyme Anti-Inflammatories. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Plaquenil and dizziness DailyStrength
     
  8. Greshnick Well-Known Member

    Lysosomotropic agents impact on lysosomal membrane. Such substances are referred to as lysosomotropic agents, and via this mechanism, trapped substances may accumulate to concentrations hundredfold that of the cytosolic concentration 22 Figure 1. Several well-known drugs used in the clinic have documented lysosomotropic abilities including the antimalarial drug chloroquine, several

    Chloroquine analogues in drug discovery new directions of.
     
  9. comerer New Member

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