Prophylaxis: 600 mcg PO within 1 minute of delivery Treatment: 800 mcg PO once; use caution if prophylactic dose already given and adverse effects present or observed Use only in settings where oxytocin not available Bacterial infections reported after use Patients must seek medical attention if excessive bleeding occurs Administration to pregnant women can cause abortion, premature birth, or birth defects Uterine rupture has been reported when drug is administered to pregnant women to induce labor; risk of uterine rupture increases with advancing gestational ages and prior uterine surgery, including cesarean delivery Contraindicated in pregnant women to reduce peptic ulcer risk from nonsteroidal anti-inflammatory drugs (NSAIDs) Warn patients of risk for abortion, and warn them not to give drug to others May cause diarrhea; should not be coadministered with other drugs that cause diarrhea (eg, magnesium-containing antacids) Adequate contraception is required in women of childbearing age May cause anaphylactic reaction May cause chills Unknown whether drug is safe for use in women with severe anemia Misoprostol may cause birth defects, abortion (sometimes incomplete), premature labor or rupture of the uterus if given to pregnant women Safety and efficacy in patients with cardiovascular disease, diabetes, renal impairment, or respiratory disease are not established Use with caution in women Pregnancy category: X Lactation: Drug is rapidly metabolized in mother to misoprostol acid, which is biologically active and is excreted in breast milk; although no published reports of adverse effects of misoprostol in breast-feeding infants exist, caution should be exercised when misoprostol is administered to breastfeeding women Synthetic prostaglandin E analogue parent drug that is rapidly deesterified to misoprostol acid (active metabolite) and replaces protective prostaglandins consumed with therapies that inhibit prostaglandin synthesis; inhibits gastric acid secretion and protects gastric mucosa Significantly reduces degree of fat malabsorption in patients with Extensive and rapid 1st-pass metabolism by liver to form misoprostol acid (active metabolite) Metabolites: Misoprostol acid (principal and active metabolite), dinor and tetranor metabolites of misoprostol acid The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information. Als Prostaglandin-Analogon wirkt Misoprostol an den Prostaglandin-Rezeptoren der Belegzellen und hemmt die Säure- und Pepsinsekretion im Magen. Es unterstützt ferner die Abwehrmechanismen der Magen- und Darmschleimhaut, indem es die schützende Bikarbonat- und Schleimproduktion fördert. Dadurch können die durch Säureüberproduktion oder durch Schmerzmittel entstandenen Schäden im Magen oder Zwölffingerdarm verringert werden. Misoprostol bewirkt eine Kontraktion der Gebärmuttermuskulatur. Misoprostol ist ein Prodrug und wird nach oraler Gabe rasch resorbiert. Der pharmakologisch aktive Metabolit Misoprostolsäure entsteht durch Biotransformation, wobei innerhalb von 15 bis 30 Minuten maximale Plasmakonzentrationen entstehen. Die Plasmaeliminationshalbwertszeit beträgt 20 bis 40 Minuten. Misoprostol ist als Fertigarzneimittel zugelassen zur Vorbeugung und Behandlung von medikamentenbedingten Schleimhautschädigungen bzw. Cialis online buy Cheap furosemide Buy apo prednisone Trusted site to buy viagra Medscape - Indication-specific dosing for Cytotec misoprostol. Termination. See mifepristone Mifeprex drug monograph for FDA approved dosage regimen. A synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition of gastric acid and pepsin secretion, and enhances. Cytotec may interact with antacids that contain magnesium. Other drugs may also interact with Cytotec. Tell your doctor all prescription and over-the-counter. Do not take this medication if you think that you may be pregnant. It may cause abortion, premature birth, or birth defects. In rare cases, serious complications (e.g., uterine rupture) have occurred when misoprostol was used to start labor or when used in combination with another drug to cause abortion after the eighth week of pregnancy. These complications have resulted in harm to the unborn baby and mother. Avoid pregnancy while taking misoprostol and for at least one month or one completed menstrual cycle after you have stopped treatment. If you become pregnant while taking misoprostol, contact your doctor right away. If you are pregnant, do not take this medication to reduce the risk of stomach ulcers due to aspirin or other related drugs (non-steroidal anti-inflammatory drugs-NSAIDs such as ibuprofen). The best and safest way a woman can do an abortion herself until the 12th week of pregnancy is with the use of two medicines called Mifepristone (also known as the abortion pill, RU 486, Mifegyn, Mifeprex, Zacafemyl), and Misoprostol (also known as Cytotec, Arthrotec, Oxaprost, Cyprostol, Mibetec, Prostokos or Misotrol). If you live in a country where there is no access to safe abortion services and you would like to obtain a medical abortion with Mifepristone and Misoprostol, please go to Women on Web ( There are 2 ways to do a medical abortion safely and effectively: To obtain a medical abortion with Mifepristone and Misoprostol, please go to Women on Web ( and do the online consultation through https:// to get a safe medical abortion using Mifepristone and Misoprostol. Women on Web is an on-line medical abortion referral service that will refer your consultation to a licensed doctor. You will also be asked to make a donation of 70, 80 or 90 euros depending on your economic circumstance and where you live, to make sure that the service continues to be available to help all women. You can make the donation using a credit card or bank transfer. If the website is blocked please send an email to:[email protected] is very important that you know how many weeks pregnant you are. Cytotec drug Cytotec misoprostol dose, indications, adverse effects, interactions., Misoprostol - DrugBank Prednisolone dose for croupMetformin tablet uses Medications are known to interact with Cytotec. Includes naproxen, calcium carbonate, magnesium oxide. Cytotec Drug Interactions -. Common Side Effects of Cytotec Misoprostol Drug Center - RxList. How many cytotec pills is neccessary to take if you want to have a.. Consumer Medicine Information CMI about Cytotec misoprostol intended for. medicines that are called non-steroidal anti-inflammatory drugs NSAIDs. Learn about Cytotec Misoprostol may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Pictures of Cytotec Misoprostol, drug imprint information, side effects for the patient.