Please review the following URL and make sure that it is spelled correctly. This article focuses upon hydroxychloroquine retinopathy. Chloroquine was originally used as an anti-malarial therapeutic. Seroquel and plaquenil interactions Anesthetic considerations for patients on plaquenil Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some. Although it is considered rare, retinal toxicity from the intake of Plaquenil can be irreversible even if the drug is discontinued 2, 3. What is Plaquenil Toxicity? The toxicity resulting from the intake of Plaquenil is due to its affinity for melanin-containing structures in the body. Cessation of plaquenil is the standard-of-care treatment for plaquenil-induced toxic maculopathy. If the patient has Possible Early Toxicity Cessation of plaquenil if possible or follow-up at 3 to 6 month intervals until there is further evidence to rule out toxicity; If the patient has Probable Toxicity In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. Color dx konan in plaquenil toxicity ColorDx Specs FAQ Register Konan Medical, Plaquenil Toxicity - Symptoms, Treatment, Risk Factors. Can plaquenil cause joint painMferg plaquenilWhen plaquenil doesn t work To reduce the incidence of chloroquine and hydroxychloroquine toxicity, health care providers HCP's that prescribe these medications and those that screen for ocular toxicity have developed clear dosing and screening protocols that have reduced the risk of end-stage disease; bull's eye maculopathy and central vision loss Level I. Chloroquine And Hydroxychloroquine Toxicity - StatPearls.. H35.381-383 Toxic Maculopathy Of Retina - Decision-Maker PLUS. ODs recognize clinical value of color vision testing. Assessment, diagnosis e.g. Plaquenil macula toxicity OU; no prior hx of color vision defects Impact on treatment, prognosis e.g. Recom-mend discontinuing Plaquenil, letter to Rheumatology Physician’s signature e.g. I. C. Better, MD Q What does Medicare allow for extended color vision testing? A CPT 92283 is per patient, not per eye. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.