Treatment is usually initiated by a specialist, but GPs play an important role in monitoring patients for adverse effects and drug interactions. This article includes a pull out DMARD monitoring table and information on tumour necrosis factor (TNF) inhibitors. What plaquenil used for Hydroxychloroquine sulfate coupons Chloroquine diphosphate in transfection Retinal toxicity and plaquenil Other DMARDs include sulfasalazine Azulfidine®, leflunomide Arava®, hydroxychloroquine. One of the side effects of leflunomide Arava, like methotrexate, is the potential for liver toxicity. Azathioprine Imuran® is indicated for rheumatoid arthritis. It is used very rarely to treat psoriatic arthritis. Before the availability of drugs like methotrexate, damage to joints and related structures from chronic inflammation associated with RA was inevitable for many patients. 1. The most widely used traditional or conventional DMARDs include methotrexate, sulfasalazine Azulfidine ®, leflunomide Arava ®, and hydroxychloroquine Plaquenil. It can either be prescribed alone or in combination with other treatments, such as methotrexate; often leflunomide is prescribed for patients who do not respond well to methotrexate. Leflunomide works by blocking the formation of DNA in the cells of your body, including those of the immune system. Dr Andrew Harrison, Senior Lecturer, Rheumatology, Wellington School of Medicine, University of Otago, Wellington Dr Rebecca Grainger, Rheumatologist and Clinical Research Fellow, Malaghan Institute of Medical Research, Wellington The aim of treatment for rheumatoid arthritis is to achieve minimal joint inflammation (a therapeutic remission). Key reviewers: Professor John Highton, Head of Section, Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago. Hydroxychloroquine methotrexate sulfasalazine azathioprine lefludomide Hydroxychloroquine Plaquenil, Traditional RA Disease modifying anti-rheumatic drugs Hydroxychloroquine sulfate tabs 200mgHydroxychloroquine related rash on external genitalia Apremilast, hydroxychloroquine, mepa-crine or minocycline. Standard monitor-ing is recommended for azathioprine, sodium aurothiomalate, leflunomide and mycophenolate mofetil, and for 12 months for sulfasalazine. Monthly monitoring should be extended long-term for ciclosporin, methotrexate plus leflunomide and tacrolimus but less frequent monitor- Prescribing and monitoring non-biological DMARDs. Treating Lupus with Immunosuppressive Medications Johns.. Traditional DMARDs Methotrexate, Leflunomide, Sulfasalazine.. Sulfasalazine may be considered Recommendation #7a – Azathioprine If hydroxychloroquine and/or methotrexate, corticosteroids, leflunomide, or sulfasalazine WEAK Sjögren’s, azathioprine may be considered. a better choice than leflunomide or sulfasalazine for the treatment of all complications including inflammatory musculoskeletal pain. Leflunomide is a new drug with a different mechanism of action than other DMARDs such as methotrexate, antimalarial drugs chloroquine and hydroxychloroquine, sulfasalazine, gold, azathioprine, d. What are the side effects of hydroxychloroquine and sulfasalazine in treating rheumatoid arthritis? ANSWER Hydroxychloroquine Plaquenil and sulfasalazine Azulfidine are used for mild.