It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine and prednisone in pregnancy Hydroxychloroquine dizziness Asprinn and plaquenil Chloroquine and depression Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. However, following an identical dose of. Not for administration with other drugs that have potential to prolong QT interval; hydroxychloroquine prolongs QT interval; ventricular arrhythmias and torsades de pointes reported in patients taking hydroxychloroquine Skeletal muscle myopathy or neuropathy leading to progressive weakness and atrophy of proximal muscle groups. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil and oral pigmentation Hydroxychloroquine-Associated Hyperpigmentation Mimicking., Hydroxychloroquine DermNet NZ Plaquenil causes lowcalcium levelsChloroquine mechanism of action lysosomeHydroxychloroquine cause bladder infectionsPlaquenil rash sun Skin Hyperpigmentation with Hydroxychloroquine. Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia, pseudopelade and discoid lupus. Skin Pigmentation with Hydroxychloroquine Plaquenil.. Plaquenil hydroxychloroquine sulfate dosing, indications.. Plaquenil - FDA prescribing information, side effects and uses. Consumer information about the medication HYDROXYCHLOROQUINE - ORAL Plaquenil, includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug HYDROXYCHLOROQUINE - ORAL. Using multivariate logistic regression, we found that HCQ-induced pigmentation was independently associated with previous treatment with oral anticoagulants and/or antiplatelet agents and with higher blood HCQ concentration. Conclusions and Relevance Hydroxychloroquine-induced pigmentation is not a rare adverse effect of HCQ. Our data support. Drug-induced pigmentation is not generally associated with any systemic toxicity and thus has an excellent prognosis. With some exceptions, pigmentation is usually reversible and slowly fades with discontinuation of the drug.