One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil liver kidney toxicity lyme Macular thinning plaquenil Buy chloroquine online Chloroquine resistance mechanism nbme 18 Jan 05, 2020 Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported 1. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Plaquenil toxicity is typically asymptomatic in early stages, but over time can lead to severe vision loss and retinal damage. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil and vision Plaquenil & Your Eyes, Plaquenil Uses, Dosage & Side Effects - Plaquenil geneticDoes hydroxychloroquine cause hair loss As a precaution, people treated with Plaquenil should get a baseline eye exam before or soon after starting the drug and visit an eye doctor ophthalmologist annually. Long term plaquenil users on high doses will need to monitor eye health regularly to prevent retinal toxicity from long-term use. How lupus affects the eyes Lupus Foundation of America. How to Succeed in Plaquenil Screenings. Taking Plaquenil for Rheumatoid Arthritis. How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Plaquenil can cause retinal damage which can be reversed if caught early. The damage to your eye would start with your peripheral vision which is why a thorough opthamalic exam and visual field test are necessary. While taking Plaquenil, a visual field test should be performed every 6 months to monitor your vision. Visual field testing is. Plaquenil can produce pigment changes in the macula of the retina. The retina is the part of the back of the eye that you see with. The macula is the central part of the retina responsible for central fine vision. With Plaquenil related toxicity, the pigment in the macula can change and alter vision by producing blurring and distortion of objects.