Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Antimalarials hydroxychloroquine What is the difference between chloroquine and chloroquine phosphate Oct findings in plaquenil toxicity The question remained, does hydroxychloroquine also prevent the development of kidney damage, one of the most serious complications of SLE? This is important to know, since patients with renal damage may need a kidney transplant or dialysis, which increase health care costs and impact patients’ quality of life.” PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. Despite optimization of renin-angiotensin-aldosterone system RAAS inhibition, patients with immunoglobulin A nephropathy IgAN and persistent proteinuria remain at risk for kidney failure. We evaluated the efficacy and safety of hydroxychloroquine HCQ, an immunomodulator, when added to the treatment regimen of patients with IgAN. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine kidney function Hydroxychloroquine - Uses, Dosage, Side Effects, Composition., Plaquenil Hydroxychloroquine Sulfate Side effects of hydroxychloroquinHydroxychloroquine 400 mg tabletsHow long does it take for chloroquine to work Kaplan-Meier survival curves as a function of hydroxychloroquine intake and WHO Class IV glomerulonephritis were also examined with renal-damage being the end-point. Results As depicted in Figure 1, 256 of the 635 LUMINA patients had renal involvement at T0 but 53 were excluded because they had already accrued renal damage. Protective Effect of Hydroxychloroquine on Renal Damage in Patients.. Effects of Hydroxychloroquine on Proteinuria in IgA.. Top Ten Drugs That Cause Kidney Damage. Background and objectives Hydroxychloroquine is widely used in patients with rheumatoid arthritis. However, large-scale studies examining the long-term effects of hydroxychloroquine on the development of kidney disease in patients with rheumatoid arthritis are lacking. We aimed to assess the long-term association of hydroxychloroquine use with the risk of developing CKD in this population. Hydroxychloroquine is a derivative of chloroquine that has both antimalarial and antiinflammatory activities and is now most often used as an antirheumatologic agent in systemic lupus erythematosis and rheumatoid arthritis. Hydroxychloroquine therapy has not been associated with liver function abnormalities and is an extremely rare cause of clinically apparent acute liver injury. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds. Because HCQ is formulated as a 200 mg tablet, many people taking it for lupus will take two pills per day.