Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. What happens when yoou stop taking hydroxychloroquine abruptly Atorvaquone vs chloroquine Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. I think tapering off over a month or so would be fine, but I would NOT go cold turkey on this one. Maybe your doc will want to switch you to another SNRI like Effexor to help during the taper off. And of course you can’t really cut the tabs in half due to the time-release coating. Plaquenil is used in the treatment of sarcoidosis but its main use is in the treatment of malaria. One of the side effects of taking the drug is that it affects eye sight, and eye tests, especially field of vision tests need to be done every six months. For the four years that I took the drug. Did you take yourself off Plaquenil, or did your doctor tell you to go off it? Plus I will be honest the whole eye site thing even though rare has always freaked me out. I went off of it to see if I can manage not being on it as my lupus isnt as severe as other cases but already I am feeling very fatigued and my legs feel heavy if that makes sense. I can discuss alternatives with my DR at my next appt but my DR feels as though the plaq is the best bet for my level of illness. If so are you just dealing with Lupus symptoms or did you take another med? I'm on Plaquenil, and after the first week's GI upset, I have had no problems with it. How to taper off plaquenil Hydroxychloroquine Oral Route Proper Use - Mayo Clinic, Want to taper off Pristiq, makes my heart race Mayo Clinic Connect Chloroquine and hydroxychloroquine for cancer therapyRetail cost of plaquenil So that's the update. The lesson here is - for those who need to go off plaquenil, be careful about just going off it cold turkey. Obviously some of CAN do that, but if you don't know if you're one of them - better to be on the safe side and wean slowly. Take it from me! I am feeling much better after bumping my dose back up over the last few. Let me tell you what weaning down from Plaquenil is like.. Plaquenil Withdrawal – Life As An Anomaly. Going off Plaquenil - Sclero Forums MAIN - Sclero Forums. I have been taking Plaquenil 400 mg per day for about 2 years now due to lupus flare. When i first started it, I was also started on prednisone to get my inflammation under control. Actually I started on 200 mg per day and about 2 months before tapering off pred, he upped me to 400 mg per day of plaquenil to give it plenty of time to kick in. Has anyone's doctor suggested taking plaquenil to help taper off Rheum thinks that plaquenil will help me get to a lower dose of prednisone since I can't get past 7.5 mg without a flare. How do you wean yourself off of hydroxychloroquine? Asked by PawPaw1234 Updated 29 October 2012 Topics hydroxychloroquine, nabumetone, period. I'm currently wanting to stop taking this product aong with the nabumetone, I am wanting to discontinue use of both meds, should I stop abrutly or wean myself off over a period of time?