It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Chloroquine lysosome inhibitor mechanism Corticosteroids vs plaquenil Effects of ultraviolet ray on chloroquine Hydroxychloroquine can cross the placenta, but appears to have no effects on congenital defects, fetal death, or prematurity.7-9 Safety data on use of cyclosporine in pregnancy from transplant patients suggest a possible risk of preterm birth and low birth weight but no congenital defects. Thiopurines, azathioprine or mercaptopurine, are. Chloroquine appears to have a deleterious effect on sperm quality in vitro and in vivo in animal studies. Little data are available in males, unlike in pregnant women in which there is a large amount of reassuring data. The teratogenic risk related to the use of hydroxychloroquine is very low. Teratogenic Effects Human pregnancies resulting in live births have been reported in the literature and no increase in the rate of birth defects has been demonstrated. Embryonic deaths and malformations of anophthalmia and microphthalmia in the offspring have been reported when pregnant rats received large doses of chloroquine. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Hydroxychloroquine teratogenic effects Hydroxychloroquine Oral Uses, Side Effects, Interactions., Immunosuppressive drugs and fertility Adverse reactions to chloroquinePlaquenil testing aaoChloroquine choleraSymptoms of plaquenil allergyHydroxychloroquine side effects rash pictures Leukeran -- Teratogenic Agent There is evidence to indicate that exposure to Leukeran a chemotherapy drug during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. Glossary for Hydroxychloroquine -- Teratogenic Agent.. DailyMed - HYDROXYCHLOROQUINE SULFATE tablet. Hydroxychloroquine - Side Effects, Dosage, Interactions.. These results raise the question of whether HCQ has any teratogenic or toxic effects. Although chloroquine inhibits DNA–RNA and DNA–DNA polymerases and, at high doses, has teratogenic effects in animals, chloroquine‐ or HCQ‐induced malformations in What are some other side effects of Hydroxychloroquine? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away Dizziness. Headache. Feeling nervous and excitable. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes.