Plaquenil and diabetic retinopathy

Discussion in 'Chloroquine 150 Mg' started by DASTY, 11-Mar-2020.

  1. Ecugool Guest

    Plaquenil and diabetic retinopathy


    She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation.

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    Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. The quinine family of drugs has been used for a variety of conditions, and Hydroxychloroquine Sulphate Plaquenil is a valuable drug for the treatment of certain auto-immune collagen-vascular disease processes. Rheumatoid Arthritis RA and Systemic Lupus Erithematosus SLE are conditions for which Hydroxychloroquine has been found to be of help.

    Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use.

    Plaquenil and diabetic retinopathy

    Screening and Management of Hydroxychloroquine Retinopathy., Hydroxychloroquine-Induced Retinal Toxicity - American.

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  7. With diabetes, the blood vessels supplying the retina and other parts of the eye become fragile and compromised. The retinopathy related to plaquenil use is actually from a kind of deposit that forms on the surface of the retina and in advanced cases, takes a "bulls-eye" shape that can be seen on exam.

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    A study of 12 patients with hydroxychloroquine retinopathy and 103 patients being treated with hydroxychloroquine but without retinopathy reported a sensitivity of 85.7% for 10–2 VFA and 78.6% for SD-OCT, and specificities of 92.5% and 98.1%, respectively. Hydroxychloroquine HCQ is an antimalarial agent that is commonly used to treat rheumatoid arthritis RA and systemic lupus erythematosus SLE. The present report documents a case of hypoglycaemia due to HCQ in a patient with SLE and diabetes mellitus type 2, in which the HCQ completely replaced the need for daily subcutaneous insulin. HealthDay—Hydroxychloroquine HCQ blood levels are useful in predicting retinopathy among patients with systemic lupus erythematosus SLE, according to a study published online Sept. 18 in.

     
  8. Sebastano New Member

    The purpose of this study is to compare the incidence of congenital defects, spontaneous abortions, number of live births, fetal death and pre-maturity in women with autoimmune diseases taking HCQ during pregnancy. List of Sjogren's Syndrome Medications 5. - Model organism - Wikipedia COPE Disclosures Plaquenil Toxicity Update
     
  9. galkac User

    Buy Prescription Hydroxychloroquine Sulfate Plaquenil. Hydroxychloroquine, generic name for Plaquenil, is commonly used to treat Malaria, Rheumatoid Arthritis, Lupus, and other immune disorders. Hydroxychloroquine is usually taken twice daily with food to minimize stomach upset, but dosing can be different based on diagnosis.

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  10. TNVF Moderator

    Plaquenil hydroxychloroquine sulfate dose, indications, adverse. Hydroxychloroquine can lower the seizure threshold; therefore, the activity of antiepileptic drugs may be impaired with concomitant use. Fingolimod Major Avoid coadministration of hydroxychloroquine and fingolimod. Hydroxychloroquine increases the QT interval and should not be administered with other drugs known to prolong the QT interval.

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