I am very underweight and do have chronic diarrhea, but gosh, this seems invasive as a first step in trying to figure out . Has anyone had chronic diarrhea/weight loss from Plaquenil? Plaquenil dosage for discoid lupus Plaquenil pulmonary hypertension 2016 ophthalmology journal hydroxychloroquine Aug 14, 2017 According to Drugs.com, Plaquenil given for a long term can cause retinal disorders after a few months or years of daily use--especially if the dose exceeds 400mg per day. The risk of retinal damage increases at doses of 600mg to 700mg. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. My rheumatologist nor the GI doctor have suggested alternate treatments to see if it could be the problem. I know it can be a temporary side effect for some, but I've been on it for a year. Does plaquenil cause diarrhea Taking Plaquenil for Rheumatoid Arthritis, Common and Rare Side Effects for Plaquenil Oral Plaquenil and vision If a stomachache does occur, it is usually temporary. However, if you experience stomach upset while taking generic hydroxychloroquine, ask your doctor about trying name-brand Plaquenil instead. While these medications contain the same active ingredient, the preparation of generic hydroxychloroquine can sometimes cause stomach irritation. Plaquenil side effects - kidney problems? - Symptoms.. Long-Term Side Effects of Plaquenil for Rheumatoid.. Plaquenil Uses, Dosage & Side Effects -. What is hydroxychloroquine Plaquenil, Plaquenil Sulfate, Quineprox? Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. I understand these may go away. Is there anything I can.