Long-term progression of hydroxychloroquine retinopathy off the drug

Discussion in 'Chloroquine Pills' started by ramdex, 03-Mar-2020.

  1. Prior Well-Known Member

    Long-term progression of hydroxychloroquine retinopathy off the drug


    Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.

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    The present study reports data on 11 cases of hydroxychloroquine retinopathy that were monitored for 13 to 51 months after cessation of the drug. These cases are identical, with those studied previously with clinical data, although several now have a longer period of follow-up. IMPORTANCE Hydroxychloroquine sulfate is widely used for the long-term treatment of autoimmune conditions but can cause irreversible toxic retinopathy. Prior estimations of risk were low but were based largely on short-term users or severe retinal toxicity bull's eye maculopathy. Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1

    Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.

    Long-term progression of hydroxychloroquine retinopathy off the drug

    Effect of Disease Stage on Progression of., The risk of toxic retinopathy in patients on long-term.

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  6. Retinopathy is uncommon if the recommended daily dose is not exceeded. It is usually reversible if therapy is discontinued. If allowed to develop, there may be a risk of progression even after treatment withdrawal.

    • Hydroxychloroquine Side Effects Common, Severe, Long Term..
    • Hydroxychloroquine toxicity - EyeWiki.
    • Hydroxychloroquine Oral Route Side Effects - Mayo Clinic.

    Hydroxychloroquine HCQ trade name, Plaquenil and chloroquine CQ trade name, Aralen are drugs established in the treatment of autoimmune disease and skin disorders, but are also emerging as a. May 16, 2011 Nevertheless, retinopathy begins to appear with long-term use, and retinopathy is serious insofar as there is no known treatment. It can progress for a year or more after stopping the drug and, if not recognized early at the point of screening, it can lead to functional blindness. The risk of toxic retinopathy in patients on long-term hydroxychloroquine therapy. JAMA Ophthalmol 2014;153–60. Wolfe F, Marmor MF Rates and predictors of hydroxychloroquine retinal toxicity in patients with rheumatoid arthritis and systemic lupus erythematosus.

     
  7. V99S New Member

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine - Wikipedia Buy Aralen chloroquine phosphate Online Blink Health Rx Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs
     
  8. losenok User

    Plaquenil and antacids? I guess I need to check into it too. I take my Prilosec about 1/2 hour to 45 minutes before Plaquenil. Last month when I was in the hospital for my hip replacement, the nurses just gave me the Prilosec with all my morning meds, including Plaquenil. I keep trying to tell them that I needed to take it earlier, but they wouldn't listen.

    Common and Rare Side Effects for Hydroxychloroquine Oral