Chloroquine route of administration

Discussion in 'Discount Prescriptions' started by suharichte, 23-Feb-2020.

  1. etlogorgru Guest

    Chloroquine route of administration


    Controlled studies in pregnant women show no evidence of fetal risk. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. Animal studies show risk and human studies not available or neither animal nor human studies done. Contact the applicable plan provider for the most current information. D: Use in LIFE-THREATENING emergencies when no safer drug available.

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    Chloroquine belongs to a class of drugs known as antimalarials. The United States Centers for Disease Control provide updated guidelines and travel recommendations for the prevention and treatment. Influence of route of administration on the pharmacokinetics of chloroquine and desethylchloroquine Article PDF Available in Bulletin of the World Health Organisation 65147-50 February. Influence of route of administration on the pharmaco-kinetics of chloroquine and desethylchloroquine. Salako LA, Aderounmu AF, Walker O. The pharmacokinetics of chloroquine following a single oral dose of 600 mg or an intramuscular injection of 200 mg of the drug was studied in seven healthy adult Africans.

    Active against erythrocytic forms of Plasmodium vivax & P. malariae and most strains of Plasmodium falciparum Precise mechanism not known Bioavailability: ~89% Peak plasma time: 1-2 hr Distributed widely in body tissues (eg, eyes, heart, kidneys, liver, lungs) where retention prolonged; crosses placenta; enters breast milk Partially in liver Half-life: 3-5 days Excretion: urine (~70% as unchanged drug); acidification of urine increases elimination Small amounts may be present in urine months following discontinuation of therapy The above information is provided for general informational and educational purposes only.

    Chloroquine route of administration

    Chloroquine Oral Uses, Side Effects, Interactions, Pictures., PDF Influence of route of administration on the.

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  7. Influence of route of administration on the pharmacokinetics of chloroquine and desethylchloroquine. This article has been cited by other articles in PMC. Abstract. The pharmacokinetics of chloroquine following a single oral dose of 600 mg or an intramuscular injection of 200 mg of the drug was studied in seven healthy adult Africans.

    • Influence of route of administration on the..
    • Influence of route of administration on the pharmaco-kinetics..
    • Route of Administration FDA.

    Oct 01, 2018 Chloroquine phosphate tablets, Chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble inwater. Irrespective of the route of administration, chloroquine is rapidly dealkylated via cytochrome P 450 into pharmacologically active desethyl chloroquine and bis-desethyl chloroquine. Desethyl chloroquine and bis-desethyl chloroquine concentrations reach 50 and 10% of chloroquine concentrations, respectively. The pharmacokinetics of chloroquine following a single oral dose of 600 mg or an intramuscular injection of 200 mg of the drug was studied in seven healthy adult Africans. Each subject received chloroquine by both routes, with an interval of at least 4 months between them.

     
  8. vsoft Moderator

    Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite. Primaquine dosing, indications, interactions, adverse. Side Effects of Primaquine Phosphate Tablets, Warnings, Uses Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs
     
  9. mitya10 Well-Known Member

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