Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Weight gain while using plaquenil Para que sirve la hydroxychloroquine 200 mg Hydroxychloroquine and lupus pregnancy Although rare, Plaquenil can cause significant toxicity to the eye with prolonged use. Also, Plaquenil may have various systemic side effects that are not related to the eyes. These too are rare and include nerve weakness, hallucinations, psoriasis and changes in hair color. The eye complications are the most serious and worrisome. The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. It succinctly makes the case for screening, and A Change In Vision; Acquired Chromatopsia, A Change In Color Vision; Irritability; Loss Of Muscle Coordination; Low Energy; Mood Changes; Muscle Tremors; Muscle Weakness; Nightmares Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Plaquenil and color vision PowerPoint. Update on Plaquenil Testing, Hydroxychloroquine And Chloroquine Screening 2016 AAO. Quarantine procedure for saltwater fish chloroquineChloroquine allergy icd 10 historyPlaquenil and respiratory problemsPlaquenil hair loss treatment Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Common and Rare Side Effects for Plaquenil Oral. How to Succeed in Plaquenil Screenings. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Then, when you stop the drug, the damage won’t progress enough to cross the fovea and affect reading vision.” Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. Ocular side effects of anti-rheumatic medications what a rheumatologist should know. A central threshold visual field and repeated color vision testing is needed with complaints of visual acuity reduction or in case of color vision changes. Fundus photography should be performed, as indicated. hydroxychloroquine sulphate Plaquenil.