Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. What does plaquenil do to the body Pct and hydroxychloroquine Hydroxychloroquine medication assistance Hydroxychloroquine azathioprine gout medications In 2005, Lareb, the Netherlands Pharmacovigilance Centre, reported that it received three reports of permanent hearing loss and tinnitus after long-term Plaquenil use. The article mentioned that hydroxychloroquine is chemically related to other drugs that have known toxic effects on hearing 2. Other Side Effects It is taken by mouth. Common side effects include muscle problems, loss of appetite, diarrhea, and skin rash. Serious side effects include problems with vision, muscle damage, seizures, and low blood cell levels. It appears to be safe for use during pregnancy. Oct 01, 2018 Cardiac Effects Cases of cardiomyopathy resulting in cardiac failure, in some cases with fatal outcome, have been reported in patients treated during long term therapy at high doses with Chloroquine see ADVERSE REACTIONS and OVERDOSAGE. Monitor for signs and symptoms of cardiomyopathy and discontinue Chloroquine if cardiomyopathy develops. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine side effects long term Hydroxychloroquine Oral Uses, Side Effects, Interactions., Chloroquine - Wikipedia Can you drink with plaquenilHydroxychloroquine sarcoidosis dosage Serious side effects and their symptoms can include the following blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or bruising. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Chloroquine - FDA prescribing information, side effects and uses. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Damage to the retina, the light sensitive portion of the inner eye, can occur with long-term use of Plaquenil or chloroquine Aralen. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. Other adverse reactions and side effects of Aralen. There have been rare reports of severe skin reactions such as erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, and exfoliative dermatitis. Chloroquine may precipitate a severe attack of psoriasis in patients with psoriasis and may worsen porphyria. The drug chloroquine has long been used to treat malaria, but it is not without side effects. Chloroquine kills malaria by causing the pH in certain parts of the parasite's cell to increase.