Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention. Plaquenil et grossesse Chloroquine mode of action malaria Borden MB, Parke AL 2001 Antimalarial drugs in systemic lupus erythematosus use in pregnancy. Drug Saf 55–1063 PubMed CrossRef Google Scholar Boström H, Moretti A, Whitehouse M 1963 Studies of the biochemistry of heart valves. On the biosynthesis of mucopolysaccharides in bovine heart valves. Hydroxychloroquine HCQ is an alkalinizing lysosomatropic drug that accumulates in lysosomes where it inhibits some important functions by increasing the pH. HCQ has proved to be effective in a number of autoimmune diseases including systemic lupus erythematosus SLE. Areas covered. Systemic lupus erythematosus is a multisystem inflammatory disease that is often difficult to diagnose. Before the diagnosis can be established, four of 11 clinical and laboratory criteria must be. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Chloroquine systemic lupus erythematosus Controlled trial with chloroquine diphosphate in systemic., PDF Hydroxychloroquine in systemic lupus erythematosus SLE Could you develop a rash 3 weeks after starting hydroxychloroquinePlaquenil monitoring labs Systemic lupus erythematosus, also known simply as lupus, is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary between people and may be mild to severe. Common symptoms include painful and swollen joints, fever, chest pain, hair loss, mouth ulcers, swollen lymph nodes, feeling tired, and a red rash which is most commonly on the face. Often there are periods of illness, called flares, and periods of remission during Systemic lupus erythematosus - Wikipedia. Diagnosis of Systemic Lupus Erythematosus. Seizures as a rare adverse effect of chloroquine therapy in.. Systemic lupus erythematosus is a condition characterized by chronic inflammation of body tissues caused by autoimmune disease. Lupus can cause disease of the skin, heart, lungs, kidneys, joints, and nervous system. When only the skin is involved, the condition is called discoid lupus. When internal organs are involved, the condition is called systemic lupus erythematosus SLE. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is also occasionally used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus. It is taken by mouth. Common side effects include muscle problems, loss of appetite, diarrhea, and skin rash. Serious User Reviews for Plaquenil to treat Systemic Lupus Erythematosus The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners.