I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. Indications of chloroquine Plaquenil and vision side effects Plaquenil warnings vision Overall I think the benefits of Plaquenil override any side effects and you hopefully can escape the nightmare known as predinisone. I also was offered methotrexate by my rheum but since I have only been on Plaquenil for 6 mos I will give it another 6mos before trying it as it scares me, the idea of taking the methotrexate. I was put on Plaquenil for RA as I was being dx for lupus. I am very mild. My rhuemy wants me to stop every time I have an infection. When it is gone she said I can resume at my own pace. Take into consideration I only take Plaquenil and ibuprofen 800mg. My symptoms came back after two weeks of being off it. If you don't have to, don't stop your plaquenil. I stopped taking the plaquenil the beginning of December. It doesn't agree with my stomach I take it with meals too. And since I hadn't had a miraculous recovery the 6 months I'd been on it, I didn't think there was any harm in stopping it. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. What will happen if i stop taking plaquenil Had to stop taking Plaquenil -, Stopping Plaquenil - General Discussion - Life With Lupus Side effects of plaquenil depressionPlaquenil cost increaseChloroquine and proguanil reviewsPlaquenil for arthritis pain2 hydroxychloroquine sulfate plaquenil sulfate Some patients decide to stop taking statins, a cholesterol-lowering drug, if they experience side effects. A new study tracked how they did. Statins What happens to patients who stop taking them.. Stopping plaquenil. DailyStrength. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. I was just curious if i was to try plaquenil again for a few days/weeks if you decide to stop do you have to wean off like a lot of drugs or can you simply stop taking it.thanks. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up.