While many of these can be grouped by anatomic location or type of toxicity, there are also individual medications with characteristic effects. In this article, we will describe several major categories of pharmacologic retinal toxicity and discuss examples of individual medications. Hydroxychloroquine brand name Relapse of plasmodium vivax after chloroquine Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Certain drugs have side effects that can lead to macular edema. Eye tumors. Both benign and malignant tumors can lead to macular edema. Eye surgery. It’s not common, but sometimes after glaucoma, retinal or cataract surgery, you can get macular edema. Injuries. Trauma to the eye. Both medications have been shown to bind melanin and to concentrate in the iris, ciliary body and retinal pigment epithelium, altering normal physiologic function. Chloroquine (Aralen) and hydroxychloroquine (Plaquenil) are traditional antimalarial agents now used in the treatment of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Plaquenil macular edema Macular degeneration and lupus" Lupus Community - Support Group, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Hydroxychloroquine and famotidineCanadian pharmacy plaquenilChloroquine vs atovaquonePlaquenil brittle hair Black white green blue red orange yellow navi. Underline links. Clear cookies Plaquenil in Los Angeles, CA Macula and Retina Institute. What Causes Macular Edema? - American Academy of Ophthalmology. Plaquenil Macular Degeneration Association. Nov 01, 2007 The syndrome is characterized by headache, nausea, vomiting, tremor, hypotension, and loss of consciousness and is associated with profound vision loss, which may be irreversible. 27 There is mild retinal edema and venous dilation in the acute phase. Over several weeks, arteriolar attenuation and optic atrophy develop. Dec 17, 2019 Depending on the cause of the macular edema and the treatment plan your doctor has recommended, the macular edema may take several months to resolve. During this time, it is important to follow the treatment regimen that your ophthalmologist recommends in order for your treatment to be effective. Nov 01, 2015 H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus.